Author Archives: Stephen

Facebook gives you cancer and infantilises the population. Ahem.

“There is no evidence because it would be hard to prove…” Aduh.

BadScience hero Ben Goldacre and Jeremy Paxman take on Baroness Greenfield, The Daily Mail (always a good target) and Aric Sigman in this interview from Newsnight. For a bit of background this is all a response to this story from the Daily Mail: http://www.dailymail.co.uk/health/article-1149207/How-using-Facebook-raise-risk-cancer.html

If you’re in my class, the page you need to comment on is here.

The Daily Mail reports  Sigman is claiming (without any real evidence) that time on the computer takes you away from real people. This makes you isolated and lonely and means you are not producing the right hormones and your genes will act up – potentially leading to cancer, immune problems and impaired mental function. That’s a far reach for a newspaper article to be making, but these kind of shock headlines sell papers, or get more traffic on their website.

In this debate we see the importance of peer-reviewed research before making public claims. We see that correlation does not necessarily imply causality and we see that poor reporting of sensitive issues can lead to gross misunderstandings. If we remember, the Daily Mail was central in the reporting of the MMR vaccine scare.

When you watch this interview and read the article, can you think of responses to these questions?

– Are there parts of Sigman and Greenfield’s claims that might sound plausible?

– What kind of evidence would you want to see to support these claims?

– What is the significance of Goldacre’s comment “… you can make anything look dangerous if you are selective in which evidence you quote” ?

– Sigman makes a comment “The paper weas supposed to be a one-sided provocative feature article for The Biologist to make people think more carefully about where society is going.” How does he feel about the media attention that his words have attracted outside this publication?

– Central to Sigman’s claims were that internet use increases social isolation. He had no peer-reviewed work after 1998 to support this, yet Goldacre pointed out all these references that suggest otherwise.

– Sigman tries to re-state ‘social networking’ as a phrase meant for real-life interactions between people rather than internet-based interactions. How has his interpretation of the term led to confusion in the wider public? Who do you think is responsible for this confusion and how could it be rectified?

– Sigman tries to distance himself from the headlines and the conjectures of Greenfield and returns to his concern that internet use is having a direct and negative impact ont the lives of children. Take this opportunity to discuss the benefits and potential negative impacts of the internet with regard to childhood use.

– Goldacre makes a comment that it woudl be bad for research to prioritse what research is done based on the headlines in the newspapers. Do you agree/ disagree? Why?

– How do you think the precautionary principle might relate to the decisions parents make based on this issue?

How would you like to see this story develop? What further research would convince you of the harms or otherwise this debate?

The Kidney

Last topic for the HL Students!

The Kidney is great – it filters our blood, makes urine and ties together so many aspects of the course – cells, membrane transport, osmosis, chemistry of life, hormonal control. We can look at how it is similar to and different from the liver and how its structure reflects its function. I love the kidney.

Here’s the presentation, with some data-y questions at the end.

More resources here:

Best kidney animation ever from biologymad.com

Quick guide to thekidney from kidneypatientguide.org.uk

Complete tutorial from Sumanas

Bilingual (Chinese and English) guide to the kidney, with rave tunes from hkedcity.net

More Loop of Henle action from the University of Colorado

Hormonal control of ADH from McGraw Hill

Diabetes recap from MedMovie

Kidney quiz from ZeroBio

Want to see a kidney stone?

Find out more about kidney stones here.

Muscles and Movement

Click4Biology page here.

Nerves, Hormones and Homeostasis

The final topic for Standard Level!

For updated versions of this post (and more to do with drugs), please click here:

Nerves, Hormones and Homeostasis

Neurotransmitters, Synapses and Drugs

As usual, click on the shadowed images to see an animation.

Introduction to the nervous system

YouTube video:

Loads of useful resources from Neuroscience for Kids

Reflex arc animation from msjensen.

Nerve impulses: resting potential and action potential

Cool tutorial from the Harvey Project

McGraw Hill nerve impulse animation

Nice and simple from mrothery

Another good one from Alberta Psychology

Propagation on myelinated and non-myelinated nerves from Blackwell Publishing

Synaptic Transmission

Great animation from McGraw Hill

Good tutorial from Harvard Outreach

Another WHS Freeman tutorial (lifewire)

The Endocrine System

Good visual introduction from Delmar Learning

Really good animation – lots of info – from e-learning for kids

Homeostasis

Tutorial and game from think-bank

Detailed tutorial from the University of New South Wales

Homeostasis in Newfoundland from Memorial University

Another good Freeman tutorial

Blood Glucose and Diabetes

MedMovie introduction

WebMD guide to diabetes

Attenborough on Darwin: The Tree of Life

This is on my shopping list for sure – and one of those rare occasions I miss British TV. Attenborough kicks the Year of Darwin off with his new documentary, The Tree of Life. Sadly the BBC iPlayer thingy is only available in the UK, though I’m sure some will know how to fool it – if you hurry there are a few days left to download it!

Here’s the man himself (Attenborough, not Darwin – that would be cool) in an interview with Nature magazine:

And if you’re up for an interesting quick read, here are the Top Ten Myths of Darwin from The Rough Guide to Evolution blog.

Gas Exhange: Core and FHP

Almost there for standard levels – just two more little topics!

Here’s the Core presentation:

And here’s the one for Further Human Physiology:

Download it here: gas-exchange-fhp.ppt

And here’s the Click4Biology page

Gas exchange, oxygen dissociation and myoglobin:

Some useful tutorials from GetBodySmart

For a quick view of some basics, here is an animation from Wisconsin Online (though it’s not very good…)

Asthma and Lung Cancer (though we don’t need lung cancer any more):

What’s asthma all about? from whatsasthma.org

Asthma attack animation from 1on1health

Lung Cancer animation from Discovery’s Human Body Atlas

Mesothelioma (caused by asbestos) from MedIndia.com

Healthy cilia and Smokers’ cilia from The Bioscope Initiative

Effects of pollution on your lungs from airinfonow.org

Some cool videos after the jump…

Read the rest of this entry

Enzymes (Core and AHL & C2)

Covering the core and AHL/ SL Option C content, here is a rundown of enzymes, from active sites to end-product inhibition. Again, there are lots of animation resources out there, many of which are used in the presentation – click on the shadowed images to go there.

Check out this article on the potential use of an enzyme in second-generation biofuels.

Enzyme Basics:

What is an enzyme? from Northland (the best one – including inhibitors, pathways and feedback inhibition)

How enzymes work from McGraw Hill

Enzyme basics from KScience.co.uk

A full collection of savable enzyme animations from Husam Medical

And John Giannini’s Enzyme collection is nice and clear.

Enzyme activity and kinetics

Nice virtual lab from KScience.co.uk

Enzyme kinetics from Wiley Interscience

Denaturation:

Protein denaturation from McGraw Hill

Inhibition

Complete tutorial from Wiley Interscience

What is an enzyme? from Northland

Feedback (end product) inhibition from McGraw Hill

And here’s a quick run down on YouTube:

Protein Synthesis: Transcription and Translation (2009)

This is a re-post for the class of 2009 to revise and the 2010 group to catch on the first time… As always, click on the shadowed images for a link to an animation, or visit the links posted below.

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Core (for everyone):

Click4Biology page

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Additional Higher Level:

Click4Biology page: TranscriptionTranslation

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Further resources:

There are many decent Flash animations and the like on the internet, but the majority cannot be embedded. Below this YouTube video, there are some direct links to resources, some of which can be easily saved.

Learn.Genetics @ Utah

Transcribe and Translate (good, basic, interactive)

How do fireflies glow? (puts it in context)

University of Nebraska:

Protein Synthesis overview (Good enough for SL)

Transcription Details (fits DP Bio HL very well)

Translation Details (fits DP Bio HL very well)

John Kyrk: (visit the parent site at www.johnkyrk.com – excellent)

Transcription (fits DP Bio HL very well)

Translation (fits DP Bio HL very well)

St. Olaf College

Transcription (clear and simple)

Translation (clear and simple)

EDIT:  Two more animations (from mrhardy’s wikispace, original source unknown)

Transcription

Translation

WH Freeman

RNA Splicing tutorial (HL only)

Bio3400

Translation with a genetic code dictionary (shows position in the ribosome)

Some more in-depth animations (newly added):

Translation from Wiley Interscience

Translation from LSU Medschool

Translation from The Chinese University in Hong Kong

Protein targeting from Rockefeller University

The Transport System (Core and HL-FHP)

The Transport System (Core)

Click4Biology page here.

And loads of useful links from North Harris College.

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Higher Level Students:

Download here: transport-system.ppt

And here’s the Click4Biology link

Medmovie.com has a large collection of animations which are great for this unit. We can’t link to them directly, but it’s worth having a look around.

The Cardiac Cycle:

Hyper Heart animation and graphs from the Chinese University of Hong Kong

Biointeractive from the Howard Hughes Medical Institute

Control of the Heart Beat:

A few good links to try from Washburn Rural High School

And don’t forget the Medmovie resource…

Atherosclerosis and Coronary Heart Disease:

Medmovie has good animations for atherosclerosis, heart attacks and heart bypass surgery. There aren’t many that are better…

Production of Tissue Fluid and Lymph:

Hydrostatic and osmotic pressure (fluid exchange) from McGraw Hill

Capillary exchange from coolschool.ca (they have other good resources, too)

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Bonus features:

For a good (tricky) prac, here’s a virtual EKG package from skillstat.com

And here’s a decent heart structure tutorial from Gateway Community College

And why not have a go at open heart surgery from abc.net.

DNA Replication (Core and AHL)

This topic is well-resourced on the internet – almost too well! Standard level students need to know the bare basics, which equates to the process of replication of the leading strand for the HL students. Here is the presentation, with some good links to follow:

DNA Replication animations:

St. Olaf’s nice and clear animation.

Another clear one from Wiley.

Nicely illustrated one from Harvard.

John Kyrk’s complicated molecular animation.

The Meselsohn Stahl experiment from Sumanas.

More animations from North Harris College and from LearnersTV.

Revision materials:

Click4Biology pages: Core & HL

Wikipedia page

Here is the top-rated video on the subject on YouTube: