Category Archives: IBDP Biology

Carbohydrates, Lipids and Proteins

Here’s the class presentation – click the shadowed images for animations.

For more information on condensation and hydrolysis reactions:

Simple explanation by Terry Brown

Collection of examples from North Harris College

Carbohydrates:

Explanation and animation from National Louis University

Proteins:

Life Cycle of a Protein from Sumanas

Making polypeptides from John Kyrk

Lipids:
Structures of Fats from HHMI

Lipids (and condensation animation) from National Louis University

Secrets of the Sequence – The Discovery of DNA

This 9-minute clip is an ideal ‘watcher’ to go along with the reader in the Course Companion – it tells the story of the discovery of the DNA double helix structure by Watson and Crick and how their discovery was dependant on the prior work of Rosalind Franklin and the compeitive/cooperative nature of research:

This clip  is taken from the vdeo lesson resource provided by Virginia Commonwealth University’s ‘Secrets of the Sequence’ website. They have 50 different videos, each with accompanying lesson plans and activities.

They also have a YouTube channel: VCULifeSciences.

Stem cells used in trachea transplant

Doctors have successfully used stem cells in a rejection-free transplant of a trachea.

This is a great example of internationalism in science – the patient was Colombian, the hospital in Barcelona, stem cells cultivated in Bristol and the final stage of the windpipe construction completed in Milan.

Check your understanding:

Did they grow a new trachea from scratch?

How did they prevent rejection of the tissue?

There is a good short reader on the NewScientist website.

The original research paper was published by The Lancet.

And another video on National Geographic.

Bio-Alive: a huge resource of animations and videos

Bio-Alive Biology and Life Sciences has a massive set of links to online tutorials, videos, animations, interactives, lectures and games. Huge. Loads.

One of the highlights has to be the video archive of surgical operations!

Follow these links for IB topic help:

Cells: animationstutorialsvirtual labslectures

Chemistry of Life: animationstutorialslectures

Genetics: animationstutorialsvirtual labslectures

Evolution: animationstutorialsvirtual labslectures

Or just visit their page for masses of links.

Foldit – help science by playing a game

Foldit is ridiculously addictive.

It is a protein-folding game/simulation, designed and produced collaboratively between the University of Washington’s Computer Science and Engineering and Biochemistry departments. There is a great introduction to the roles of proteins in metabolism and disease, as well as protein folding, on their about page.

Apart from the great software and in-game tutorials in protein structures, players at the highest level may be contributing to medicine! The University and associated labs are setting problems of protein folding for players to solve – each one an important molecule in its own right and some even the key to curing some diseases.

There is a great article about the game on RichardDawkins.net: ‘Computer game’s high score could earn the Nobel prize in medicine.’ There’s even a classic quote from co-developer Prof. David Baker:

“I imagine that there’s a 12-year-old in Indonesia who can see all this in their head.”

Too right. Let’s represent for Indonesia!

Here’s a quick clip of the game in action at a high level:

Download the game here and get playing!

Mice cloned from frozen bodies

So cloning is nothing new, but for the first time we see healthy lab mice cloned from the cells of dead mice – some articles are calling this a ‘resurrection’, although it is nothing of the sort.

It is, however, a big step forward for genetic reserach – lifting the possibility of cloning long-extinct species out of the realms of pure science fiction and into the ‘almost there’ zone. A team of Japanese researchers from Kobe, Japan, used a modified method to clone these mice from tissues that had been frozen for up to 16 years.

Here’s a clip from Japanese news, with a really clear section showing what looks like the insertion of the nucleus into an egg:

For a useful reader, here is the NewScientist article. Here’s another one from the Guardian.

As ever, one of the best reading sources is the Not Exactly Rocket Science blog, where Ed Yong tackles the research paper directly in his article and makes it easy to understand. Check it out here.

Learning idea: ‘dub’ the Japanese clip into your own language, using the information from the articles above.

How did they achieve it? How does it differ from normal cloning? What surprising results did they encounter?

Try to get your story to complement the images in the video clip.

I can just see Jeff Goldblum‘s gurning face as runs for his life from a cloned dodo…

Interactive Concepts in Biochemistry

Found this useful source on North Harris College’s linklist

Wiley.com have produced this online resource for Biochemistry and the Chemistry of Life, and it contains a whole load of interactives and animations.

It is an ideal resource for: photosynthesis, respiration, DNA replication, transcription, translation, cell structure, enzymes and protein synthesis.

Microdocs: Stanford’s reef sustainability documentaries

Stanford’s Microdocs project is a well-presented set of video and pdf resources for learning about sustainability and the coral reef ecosystem. Each video is a few minutes long and accompanied by a short article or links to useful sources.

It’s divided into useful topics and easy to navigate (and looks good, too).

And while we’re on the theme of the oceans (again) there’s a brilliant student activity resource centre at the UCLA’s OceanGlobe centre. Everything you could ever need to study marine science.

Einstein the Parrot: Talking and Squawking

This is five minutes of entertainment from TED Talks:

Einstein the Parrot is an African Grey, a species known for their intelligence and ability to build a large vocabulary. As research into animal intelligence develops, it raises questions on how we measure intelligence – are we really that much more ‘intelligent’ than our philosophising cousins?

How do we discern the difference between a well-trained animal putting on a show and one which is making considered decisions on its behaviour?

For an interesting overview of animal cognition, check out this wikipedia article and do some further reading around the sources listed in the references section.

New resources at Learn.Genetics

This is via the Learn.Genetics mailing list. Why not join – they only send mails out when there’s something worth reading.

Coming soon, Amazing Cells:activities and animations on cell processes and communication.

Also, a new interactive lab activity: Polymerase Chain Reaction Biotechniques lab.