Amgen: Hi-tech Cancer Video Resources
This resource was first posted on Wired.com and looks great – if you have the bandwidth to load and play it. Amgen is a for-profit US-based biotechnology company that are working on pharmaceuticals to combat cancer and other illnesses. With this resource, including 15 videos, they show how they are working to combat tumour angiogenesis – the critical stage in cancer development which often leads to complications and mortality.
As the tumour grows, it requires a blood supply and angiogenesis provides this – by growing new blood vessels. The risk now is metastasis – some of the tumour could pass into the new blood vessels and be carried around the body, where they might reinvade and grow in a new location. Metastasis accounts for the majority of deaths related to cancer.
To enter their flashy angiogenesis website, click here.
Or for a sneaky peaky:
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There are also some good angiogenesis animations on YouTube, which might load more easily:
A longer explanation from Envita healthcare:
And for loads of great information, the National Cancer Institute has a series of slides with information, and a powerpoint presentation free to download.
Tonga Boom! Undersea volcano erupts off Tonga
Imagine being on a fishing boat making a holiday video and then the whole ocean explodes around you. Well that’s not exactly what happened, but it would be a good story…
According to the Global Volcanism Program, this volcano started to erupt on the 16th or 17th March and has been going since. This video shows a team of scientists who took their boat out to the site to capture footage and record local and wide-spread changes. Apparently, no-one has been hurt by the volcano.
To see some aerial photos of the volcano, with coordinates, visit the ASTER volcano archive.
Click on the image below for some great photos from the Guardian.
As you can see, the plume of ash and steam is huge. A line from the AP states “the eruption does not pose any danger to islanders at this stage, and there have been no reports of fish or other animals being affected” – other than by the great big explosion, then.
To learn more about volcanoes in general, visit the Science Education Resource Centre’s Volcano visualisation library. For more about how underwater volcanoes are monitored, check out this flash animation from NeMO Net, from NOAA.
For another good article on vocanoes, click on the image below to see what Wired.com has to say…
NOAA Environmental Visualisation Library
Awesome. NOAA (National Oceanographic and Atmospheric Administration) has revamped its Environmental visualisation libray – bringing new educational materials, visualisations, animations and resources to educators and the public. See the images of the 2008 hurricane season, animations of the ocean damage caused by humans or check out their library of satellite images.
They also have a YouTube channel where you can view and download some of their video resources. In relation to our upcoming Earth Day theme of “Reefs and Oceans“, here’s a clip about the effects of coral bleaching:
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How to regrow a rainforest – Willie Smits on TED Talks
My Grade 12 class have looked at this story before, and now we can hear about it from Willie Smitts, a primatologist and conservationist who has led a huge project to replant and revive a section on rainforest in Borneo. They have taken over 8,000 hectares of scorched and cleared land and are returning it to a habitat worthy of orang-utans and many more endangered species.
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Smits was featured in TED2009 and here he is with his story of how they regrew the rainforest.
Science and Islam – BBC4 Series
I heard about this series on BBC 4 when listening to the Guardian Science Weekly podcast recently. They had the presenter and physicist, Jim Al-Khalili, on the show talking about some of the great discoveries and advances made in the Islamic world between the 8th and 14th Centuries.
Think about it this way – if it has an ‘al’ at the beginning, there’s a fair bet that it was discovered, invented or pushed forward in the Islamic world: algebra, algorithms, alkali, alcohol…
Alhazen (Ibn al-Haythem) is considered one of the founders of the scientific method which we still use today – a good scientist formulates a hypothesis and devises a method to prove it wrong. In this way, we know if a scientific idea stands up to testing. If not, we need to revise the hypothesis and test again.
You can see the official BBC page for the programme here, but the video may no longer be available to download. Alternatively, pick up the episodes (broken into parts), from YouTube:
1: The Language of Science
Part 1, Part 2, Part 3, Part 4, Part 5, Part 6
2: The Empire of Reason
Part 1, Part 2, Part 3, Part 4, Part 5, Part 6
3: The Power of Doubt
Part 1, Part 2, Part 3, Part 4, Part 5, Part 6
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To find out more about Science and the Islamic world, try some of these resources:
1001 Inventions: a great resource for Science and Tech discoveries
Facebook gives you cancer and infantilises the population. Ahem.
“There is no evidence because it would be hard to prove…” Aduh.
BadScience hero Ben Goldacre and Jeremy Paxman take on Baroness Greenfield, The Daily Mail (always a good target) and Aric Sigman in this interview from Newsnight. For a bit of background this is all a response to this story from the Daily Mail: http://www.dailymail.co.uk/health/article-1149207/How-using-Facebook-raise-risk-cancer.html
If you’re in my class, the page you need to comment on is here.
The Daily Mail reports Sigman is claiming (without any real evidence) that time on the computer takes you away from real people. This makes you isolated and lonely and means you are not producing the right hormones and your genes will act up – potentially leading to cancer, immune problems and impaired mental function. That’s a far reach for a newspaper article to be making, but these kind of shock headlines sell papers, or get more traffic on their website.
In this debate we see the importance of peer-reviewed research before making public claims. We see that correlation does not necessarily imply causality and we see that poor reporting of sensitive issues can lead to gross misunderstandings. If we remember, the Daily Mail was central in the reporting of the MMR vaccine scare.
When you watch this interview and read the article, can you think of responses to these questions?
– Are there parts of Sigman and Greenfield’s claims that might sound plausible?
– What kind of evidence would you want to see to support these claims?
– What is the significance of Goldacre’s comment “… you can make anything look dangerous if you are selective in which evidence you quote” ?
– Sigman makes a comment “The paper weas supposed to be a one-sided provocative feature article for The Biologist to make people think more carefully about where society is going.” How does he feel about the media attention that his words have attracted outside this publication?
– Central to Sigman’s claims were that internet use increases social isolation. He had no peer-reviewed work after 1998 to support this, yet Goldacre pointed out all these references that suggest otherwise.
– Sigman tries to re-state ‘social networking’ as a phrase meant for real-life interactions between people rather than internet-based interactions. How has his interpretation of the term led to confusion in the wider public? Who do you think is responsible for this confusion and how could it be rectified?
– Sigman tries to distance himself from the headlines and the conjectures of Greenfield and returns to his concern that internet use is having a direct and negative impact ont the lives of children. Take this opportunity to discuss the benefits and potential negative impacts of the internet with regard to childhood use.
– Goldacre makes a comment that it woudl be bad for research to prioritse what research is done based on the headlines in the newspapers. Do you agree/ disagree? Why?
– How do you think the precautionary principle might relate to the decisions parents make based on this issue?
How would you like to see this story develop? What further research would convince you of the harms or otherwise this debate?
The Kidney
Last topic for the HL Students!
The Kidney is great – it filters our blood, makes urine and ties together so many aspects of the course – cells, membrane transport, osmosis, chemistry of life, hormonal control. We can look at how it is similar to and different from the liver and how its structure reflects its function. I love the kidney.
Here’s the presentation, with some data-y questions at the end.
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More resources here:
Best kidney animation ever from biologymad.com
Quick guide to thekidney from kidneypatientguide.org.uk
Complete tutorial from Sumanas
Bilingual (Chinese and English) guide to the kidney, with rave tunes from hkedcity.net
More Loop of Henle action from the University of Colorado
Hormonal control of ADH from McGraw Hill
Diabetes recap from MedMovie
Kidney quiz from ZeroBio
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Want to see a kidney stone?
Find out more about kidney stones here.








