This is an interesting discussion starter and is only 11 minutes long. Boghuma Kabisen Titanji talks about the ethical dilemmas of HIV research in developing countries. What happens when the trial ends?

Some discussion ideas:

• Discuss the pros/ cons of testing pharmaceuticals in the developing world vs the ‘west’.
  • Authorisation of trials
  • Risk of litigation
  • Willingness of populations to participate
  • Potential sample size
  • Ethics vs efficiency in data generation
  • Cost-benefit ratio
• Outline what is meant by ‘informed consent’ in terms of clinical trials. Discuss the challenges of informed consent in trials in the developing world.
• Evaluate the suggestions Boghuma Kabisen Titanji makes about:
  • Informed consent
  • Standard of care provided to participants
  • Ethical review of research
  • Exit plan – what happens to participants once the trial has ended?